Vasopressin should be given to a pregnant woman only if clearly needed.Doses of vasopressin sufficient for an antidiuretic effect are not likely to produce tonic uterine contractions that could be deleterious to the fetus or threaten the continuation of the pregnancy.Caution should be exercised when vasopressin is administered to a nursing woman.Local or systemic allergic reactions may occur in hypersensitive individuals. Vasopressin injection is also used to prevent and treat abdominal or stomach distension that occurs after surgery. When you are taking vasopressin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Vasopressin injection is also used to prevent and treat abdominal or stomach distension that occurs after surgery. Follow the instructions carefully to prevent unwanted effects.The dose of vasopressin will be different for different patients.
Vasopressin has a plasma half-life of about 10 to 20 minutes. Abdominal Roentgenography: For the average case, 2 injections of 10 units (0.5 mL) each are suggested. Use a different body area each time you give yourself a shot. (For an additional discussion of dosage, consult the sections below.
For use in diabetes insipidus, when this is not of nephrogenic origin and control of bleeding from oesophageal varices. Vasopressin may produce water intoxication. Spontaneous recovery from such side effects occurs in a few minutes. Glacial acetic acid and/or sodium hydroxide may have been added for pH adjustment (2.4-4.5).The antidiuretic action of vasopressin is ascribed to increasing reabsorption of water by the renal tubules.Vasopressin can cause contraction of smooth muscle of the gastrointestinal tract and of all parts of the vascular bed, especially the capillaries, small arterioles and venules with less effect on the smooth musculature of the large veins. The early signs of drowsiness, listlessness and headaches should be recognized to prevent terminal coma and convulsions.Vasopressin should be used cautiously in the presence of epilepsy, migraine, asthma, heart failure or any state in which a rapid addition to extracellular water may produce hazard for an already overburdened system.Chronic nephritis with nitrogen retention contraindicates the use of vasopressin until reasonable nitrogen blood levels have been attained.Side effects such as blanching of skin, abdominal cramps, and nausea may be reduced by taking 1 or 2 glasses of water at the time of vasopressin administration. Vasopressin injection is also used to prevent and treat abdominal or stomach distension that occurs after surgery. It acts on the kidneys to reduce the flow of urine.Vasopressin injection is also used to increase blood pressure in adults with vasodilatory shock (eg, post-cardiotomy, sepsis) who remain to have low blood pressure after receiving fluids and medicines.Vasopressin is available only with your doctor's prescription.In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. These recommendations apply also to distention complicating pneumonia or other acute toxemias. Using alcohol or tobacco with certain medicines may also cause interactions to occur.
Following subcutaneous or intramuscular administration of Vasopressin injection, the duration of antidiuretic activity is variable but effects are usually maintained for 2 to 8 hours.
The dose by injection is 5 to 10 units (0.25 to 0.5 mL) repeated two or three times daily as needed. For vasopressin, the following should be considered:Tell your doctor if you have ever had any unusual or allergic reaction to vasopressin or any other medicines. 20 international units argipressin (vasopressin) per ml.).
Vasopressin is also used to treat or prevent certain conditions of the stomach after surgery or during abdominal x-rays.
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