Cerner Multum, Inc. "UK Summary of Product Characteristics." ([2014 May]):13. AIDS 20 (2006): 1352-433. Welch KJ, Morse A "Association between Efavirenz and Selected Psychiatric and Neurological Conditions." Call your doctor for medical advice about side effects. Chest pain; confusion
Call your doctor for medical advice about side effects. "Comparison of side effects with 2 doses of the HIV drug efavirenz." It has not been found to be effective in treating psychosis. One percent of patients discontinued or interrupted therapy due to at least 1 of these side effects.Side effects of moderate or severe intensity included insomnia (up to 7%), depression (up to 5%), anxiety (up to 4%), abnormal dreams (up to 3%), and nervousness (up to 2%).Elevated amylase (greater than 2 times the upper limit of normal [ULN]) has been reported in up to 6% of patients.False-positive urine cannabinoid test results have been observed with some screening assays in uninfected and HIV-infected subjects using this drug.Increased ALT, AST, and GGT to greater than 5 times ULN have each been reported in up to 8% of patients. Pasquet A, Viget N, Ajana F, et al. Treat Guidel Med Lett 7 (2009): 11-2210. However, safety and efficacy have not been established in children less than 12 years of age. This medicine may increase your risk for bleeding problems. Drugs 61 (2001): 19-2611.
Ther Drug Monit 28 (2006): 28660.
Journot V, Chene G, De Castro N, et al. ing efavirenz and psychotropic drugs to their HIV patients. Clarke S, Harrington P, Barry M, Mulcahy F "The tolerability of efavirenz after nevirapine-related adverse events." It is most commonly used to treat fungal infections of the mouth (thrush), esophagus (the tube that takes food from the throat to the stomach), lungs, urinary tract, and vagina (yeast infection). Haas DW, Ribaudo HJ, Kim RB, et al.
However, elderly patients are more likely to have hyponatremia (low sodium in the blood) and age-related liver problems, which may require caution and an adjustment in the dose for patients receiving escitalopram.Studies in women breastfeeding have demonstrated harmful infant effects. Clin Infect Dis 31 (2000): 1266-7314. Families and caregivers should be advised of the need for close observation and communication with the prescriber.
Pharmacotherapy 22 (2002): 930-353. de La Garza CL, Paoletti-Duarte S, Garcia-Martin C, Gutierrez-Casares JR "Efavirenz-induced psychosis." This is not a complete list of side effects and others may occur. Bristol-Myers Squibb, Princeton, NJ. Other side effects not listed may also occur in some patients. Med Lett Drugs Ther 48 (2006): 78-942. If you notice any other effects, check with your healthcare professional. Clin Infect Dis 42 (2006): 408-1029. AIDS 23 (2009): 118161. This is not a complete list of side effects and others may occur. TreatmentUpdate 18 (2006): 3-430.
Clin Infect Dis 31 (2000): 806-79. Efavirenz has a long plasma half-life, which allows for once-daily dosing, but, as a consequence of this and the low genetic barrier, it is also prone to select for viral resistance when adherence to therapy is suboptimal. Ann Pharmacother (2006):55. J Antimicrob Chemother 62 (2008): 879-8847.
Call your doctor for medical advice about side effects. Let the doctor know if you or anyone in your family has bipolar disorder (manic-depressive) or has tried to commit suicide.Escitalopram may cause a serious condition called serotonin syndrome if taken together with some medicines. Clifford DB, Evans S, Yang Y, et al. The most common side effects (at least moderate severity) were impaired concentration, abnormal dreams, rash, dizziness, nausea, headache, fatigue, insomnia, and vomiting in patients using this drug in combination with lamivudine - zidovudine or indinavir. Read and follow these instructions carefully. "Drugs for HIV infection."
If you notice any other effects, check with your healthcare professional. Cerner Multum, Inc. "UK Summary of Product Characteristics."
Some people may have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Benefits support its short term use. It can cause some minor side effects such as stomach upset, headache, dizziness, constipation, ... (BuSpar)Interaction Rating: ... along with ginkgo extract might decrease the effects of efavirenz (Sustiva).
It may also cause some people to have suicidal thoughts and tendencies or to become more depressed.
Clin Infect Dis (2009):57. Fischl MA, Collier AC, Mukherjee AL, et al. Br J Clin Pharmacol 61 (2006): 148-5431. Clin Infect Dis 40 (2005): e22-339. The median time to onset of rash in adults was 11 days.
Jemsek JG, Arathoon E, Arlotti M, et al.
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